Geospatial data and Geographic Information Systems (GIS) are critical infrastructure in the United States, vital for governance, economic activity, environmental management, and national security. Effective national-level coordination is essential to manage this complex ecosystem. The Federal Geographic Data Committee (FGDC) guides the National Spatial Data Infrastructure (NSDI), a nationwide framework of policies, standards, and partnerships for geospatial data. Key federal agencies, including the U.S. Geological Survey (USGS), National Oceanic and Atmospheric Administration (NOAA), and the Department of Homeland Security (DHS), serve as primary stewards of foundational national geospatial data. The National Geospatial Advisory Committee (NGAC) provides crucial non-federal perspectives to guide these federal efforts. This entry outlines the primary federal bodies, programs, and communities of practice that constitute the U.S. national geospatial enterprise, their interconnections, and the persistent challenges they face.